In Vitro Free Radical Scavenging Activity of Methanol Extract of the Leaves of Mimusops Elengi Linn

نویسندگان

  • M. R. Saha
  • S. M. R. Hasan
  • R. Akter
  • M. M. Hossain
  • M. S. Alam
  • M. A. Alam
  • M. E. H. Mazumder
چکیده

In the present study, antioxidant potential of the methanol extract of the leaves of Mimusops elengi Linn. was evaluated by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, reducing power and total antioxidant capacity. The extract showed significant activities in all antioxidant assays compared to the reference antioxidant ascorbic acid in a dose dependent manner. In DPPH scavenging assay the IC50 value of the extract was found to be 43.26μg/ml while the IC50 value of the reference standard ascorbic acid was 58.92 μg/ml. Total antioxidant activity was also found to increase in a dose dependent manner. Moreover, M. elengi extract showed strong reducing power. These results suggest that Mimusops elengi may act as a chemopreventative agent, providing antioxidant properties and offering effective protection from free radicals.

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تاریخ انتشار 2009